Page 23 - Hikma - Oncology booklet

Dose adjustment in Renal Impairment

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> 50 mL/min
15-50 mL/min
Creatinine Clearance
Eopul 100% of dose 75% of dose

Side effects

01 Hematologic Toxicity
leukopenia (22-41%) -

anemia (0-33%) Gastrointestinal Toxicity 02

Nausea and vomiting
Allergic Reactions 31-43%
03

Chills, fever, tachycardia
Alopecia 04

Reversible (up to 66%)

Storage precaution

Unopened vials stored
under refrigeration 2°

to 8°C (36°- 46°F)

Refrigerate,

do not freeze

Pregnancy & Lactation

Pregnancy Contraindicated

Lactation Contraindicated
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