Page 48 - Hikma - Oncology booklet

Dosage con.

Meningeal Leukemia
Click to edit Master title style

Intrathecal Once every 4 days until

administration 30 CSF findings normal plus
(IT) mg/m 2 one additional dose

Refractory Leukemia

Intravenous
3 IV (over 1-3 hours)
administration g/m 2 q12hr x 4-12 doses

Dosage adjustments recommendations

Patients treated with  doses of cytarabine should be

observed for neuropathy since dose adjustments may be

needed to avoid irreversible neurologic disorders.

Side effects

Chest pain

Bone marrow failure 1 Hemorrhagic conjunctivitis
8 2

Somnolence 7 3 Sepsis

6 4
loss of appetite 5 Cytarabine syndrome

Pyrexia
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