Page 44 - Hikma - Oncology booklet

Dosage con.

Multiple Sclerosis:
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Short IV (5-15 minutes) infusion
12
mg/m 2 q3 Months. Not to exceed lifetime
cumulative dose of 140 mg/m².

Dosage adjustments recommendations

The safety in patients with hepatic/renal impairment

have not established so, it should be administered with

caution.

Side effects

1 Nausea, vomiting, heartburn, stomach pain

Diarrhea, constipation, headache, unusual
2 tiredness, hair loss

Heavy menstrual bleeding, missed menstrual
3 periods, runny nose, depressed mood

Blue-green colored urine or a bluish color of the
4
whites of the eyes for a few days after each dose

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