Page 39 - Hikma - Oncology booklet
P. 39

Indication





                                       Adjuvant treatment of stage III colon
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                                       cancer in patients who have undergone
                                       complete resection of the primary tumor.




                                       Treatment of advanced colorectal cancer.



                        Dosage



        Day 1:




                                       85                           200
          Oxaliplatin               mg/m    2                     mg/m    2         leucovorin








                                    IV infused over 2 hr, THEN







                                  400
                                mg/m    2           fluorouracil IV bolus over
                                                          2 - 4 min. , THEN










                                 600                 fluorouracil IV infusion in

                               mg/m     2
                                                     D5W (500 mL) over 22 hr






         Day 2 :


          Same regimen WITHOUT oxaliplatin ,Repeat every 2 weeks                                   1
          18/01/2020
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