Page 59 - Hikma - Oncology booklet
P. 59

Indication



                        Polyarticular Juvenile Idiopathic Arthritis (PJIA)
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                                                          2


                          1
                                                                                    3

            Acute Lymphoblastic

                Leukemia (ALL)                                                  Psoriasis




                        Dosage





                            2
              20 mg/m one-time
                        weekly




               Starting dose of 10

                    2
           mg/m one-time weekly



          10-25 mg as a single oral,
           IM, SC , or IV dose once

                       weekly


                        Drug interactions






                                         Oral Antibiotics: May  hematologic and
                                         gastrointestinal toxicity. Monitor patients

                                         accordingly.




                                         Hepatotoxins: May  risk of hepatotoxicity.
                                         Monitor patients accordingly.



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